PHARMACY MCQ AND NPC EXAM DAILY SERIES 16

                                           Logical questions with multi option answers:                                                         

1. Digitalis toxicity is enhanced by co-administration of:

(A) Potassium

(B) Quinidine 

(C) Diuretics 

(D) Antacids

2. The rate limiting step in cholesterol biosynthesis is one of the followings : 

(A) LDL-receptor concentration 

(B) VLDL secretion

(C) Mevalonic acid formation 

(D) Co-enzyme A formation 

3.Shilajit is a :

(A) Mineral drug

(B) Herbal drug

(C) Semisynthetic drug

(D) Herbosynthetic drug

4. Ganciclovir is mainly used for the treatment of infection caused by:

(A) Cytomegalovirus 

(B) Candida albicans

(C) Herpes zoster virus 

(D) Hepatitis B virus

5. Identify the one rational combination which has clinical benefit : 

(A) Norfloxacin – Metronidazole 

(B) Alprazolam – Paracetamol

(C) Cisapride – Omeprazole 

(D) Amoxycillin – Clavulanic acid     

6. Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs : 

(A) Sulphonamides 

(B) Macrolides

(C) Penicillins 

(D) Tetracyclines

7. Amitryptyline is synthesized from the following starting material :

(A) Phthalic anhydride 

(B) Terephthalic acid

(C) Phthalamic acid 

(D) Phthalimide

8. The common structural feature amongst the three categories of anticonvulsant drugs barbiturates, succinimides and hydantoins is:

(A) ureide 

(B) imidazolidinone

(C) dihydropyrimidine 

(D) tetrahydropyrimidine

9. Nicotinic action of acetylcholine is blocked by the drug:

(A) Atropine 

(B) Carvedilol

(C) Neostigmine 

(D) d-Tubocurarine 

10. Chemical nomenclature of procaine is:

(A) 2-Diethylaminoethyl 4-aminobenzoate 

(B) N,N-Diethyl 4-aminobenzoate 

(C) 4-Aminobenzamidoethyl amine 

(D) 4-Amino-2-diethylaminoethyl benzoate                                             

11. Barbiturates with substitution at the following position possess acceptable hypnotic activity :

(A) 1,3-Disubstitution 

(B) 5,5-Disubstitution

(C) 1,5-Disubstitution 

(D) 3,3-Disubstitution

12. Selective serotonin reuptake inhibitor is:

(A) Imipramine 

(B) Iproniazide 

(C) Fluoxetin 

(D)Naphazoline

13. Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system :

(A) Pyrimidine 

(B)Benzimidazole 

(C) Benzothiazole 

(D) Oxindole 

14. A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is:

(A) Fluvastatin 

(B) Cerivastatin 

(C) Lovastatin 

(D) Somatostatin

15. Cyclophosphamide as anticancer agent acts as:

(A) alkylating agent before metabolism (B)alkylating agent after metabolism

(C) phosphorylating agent after metabolism                                                                                             (D) DNA intercalating agent